Find The Cause Research Consortium
2025 Published Papers
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Find The Cause has been cited in the following high profile journal papers written by Find The Cause Research Consortium scientists. Your funding dollars have contributed directly to these discoveries.
Articles in Nature’s “Nature Reviews Cancer”:
Environmental Endocrine Disruptors: Rethinking the Origins of Early-Onset ER+ Breast Cancer
The Kuperwasser Lab at Tufts explores how rising rates of early-onset oestrogen receptor-positive (ER +) breast cancer in women without genetic risk suggest a shift in disease biology. Chronic and cumulative exposure to endocrine-disrupting chemicals may induce field cancerization in the breast, warranting urgent attention from researchers, regulators and public health leaders.
Prospects for Ferroptosis Therapies in Cancer
The Ubellacker Lab at Harvard Chan School of Public Health explain why turning ferroptosis (a unique way that cells can die) discoveries into clinical therapies for cancer has been so challenging and what strategies might make it possible in the years to come.
Articles in Other High-Level Publications:
LSD1 inhibition corrects dysregulated MHC-I and dendritic cells activation through 2 IFNγ-CXCL9-CXCR3 axis to promote antitumor immunity in HNSCC
The Monti and Varelas Labs at Boston University investigate how LSD1-mediated unique mechanisms have impact on 42 epigenetic therapy, MHC-I resistant HNSCC therapies, and poor CD8+ and dendritic cell 43 infilterated tumors.
DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation
The Monti Lab at Boston University and the Kuperwasser Lab at Tufts use a next-generation single-cell-derived organoid model to investigate how individual stem cells give rise to complex tissue to understand epithelial stem cell differentiation and morphogenesis during breast tissue development is essential, as disruption in these processes underlie breast cancer formation.
Next-Generation Breast Organoids Capture Human Organogenesis with 2 High-Resolution Live Imaging
The Kuperwasser Lab at Tufts introduces a groundbreaking organotypic culture technique that replicates the 30 morphology, scale, and heterogeneity of human breast tissue, and includes a mesenchymal-like 31 stromal component.
The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA
The Sherr Lab at Boston University investigates a novel role for an immunosuppressive environmental chemical receptor, previously implicated in smoking-related cancers, in IFN signaling in human lung adenocarcinoma (LUAD) cells.
A highly resolved integrated single-cell atlas of HPV-negative head and neck cancer
The Monti and Varelas Labs at Boston University investigate four Head and Neck Squamous Cell Carcinomas (HNSCC), which are the seventh most prevalent form 25 of cancer and are associated with human papilloma virus infection (HPV) and have a high recurrence rate. They describe a HNSCC single cell 29 atlas, which they created by integrating six publicly available datasets encompassing over 30 230,000 cells across 54 patients.
LATS1/2 inactivation in the mammary epithelium drives the evolution of a tumor-associated niche
The Monti and Varelas Labs at Boston University demonstrate that carcinomas resulting from Hippo pathway dysregulation in the mammary epithelium are sufficient to drive cellular events that promote a basal-like tumor-associated niche and suggest that targeting dysregulated YAP/TAZ-TEAD activity may offer a therapeutic opportunity for basal-like mammary tumors.
