Full Length, Peer-Reviewed Journal Articles In 2016 in Which Support from Find the Cause Breast Cancer Foundation Was Acknowledged:

Stanford, E. A., Z. Wang, O. Novikov, F. Mulas, E. Landesman-Bollag, S. Monti, B. W. Smith, D. C. Seldin, G. J. Murphy, and D. H. Sherr. 2016. The role of the aryl hydrocarbon receptor in the development of cells with the molecular and functional characteristics of cancer stem-like cells. BMC Biol 14: 20. https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0240-y

Stanford, E. A., A. Ramirez-Cardenas, Z. Wang, O. Novikov, K. Alamoud, P. Koutrakis, J. P. Mizgerd, C. A. Genco, M. Kukuruzinska, S. Monti, M. V. Bais, and D. H. Sherr. 2016. Role for the aryl hydrocarbon receptor and diverse ligands in oral squamous cell carcinoma migration and tumorigenesis. Mol Cancer Res 14: 696-706. http://mcr.aacrjournals.org/content/14/8/696.full-text.pdf

Das SG, Romagnoli M, Mineva ND, Barillé-Nion S, Jézéquel P, Campone M, Sonenshein GE. 2016. miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells. Breast Cancer Res. 18:40. https://www.ncbi.nlm.nih.gov/pubmed/27039296

Ni TK, Kuperwasser C. Premature polyadenylation of MAGI3 produces a dominantly-acting oncogene in human breast cancer. Elife. 2016 May 20;5. pii: e14730. doi: 10.7554/eLife.14730. https://www.ncbi.nlm.nih.gov/pubmed/27205883 

Sedic M, Kuperwasser C. BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancer. Cell Cycle. 2016;15(5):621-7. doi: 10.1080/15384101.2016.1141841. https://www.ncbi.nlm.nih.gov/pubmed/?term=Sedic+M%2C+Kuperwasser+C.+BRCA1-hapoinsufficiency%3A+Unraveling+the+molecular+and+cellular+basis+for+tissue-specific+cancer.+Cell+Cycle.+2016%3B15(5)%3A621-7.+doi%3A+10.1080%2F15384101.2016.1141841

Smith BW, Stanford EA, Sherr DH, Murphy GJ. Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development. Stem Cells Int. 2016;2016:2574152. doi: 10.1155/2016/2574152. Epub 2016 Apr 11. https://www.ncbi.nlm.nih.gov/pubmed/27148368 

Stanford EA., Wang Z,  Novikov O, Mulas F, Landesman-Bolag E., Monti S, Smith B, Muprhy GJ, and Sherr DH. 2016. The role of the aryl hydrocarbon receptor in the development of cells with molecular and functional characteristics of breast cancer stem cells. BMC Biology. 14:20. https://www.ncbi.nlm.nih.gov/pubmed/?term=Stanford+EA.%2C+Wang+Z%2C++Novikov+O%2C+Mulas+F%2C+Landesman-Bolag+E.%2C+Monti+S%2C+Smith+B%2C+Muprhy+GJ%2C+and+Sherr+DH.+2016.+The+role+of+the+aryl+hydrocarbon+receptor+in+the+development+of+cells+with+molecular+and+functional+characteristics+of+breast+cancer+stem+cells.+BMC+Biology.+14%3A20.

Stanford, EA, Ramirez-Cardenas A, Wang Z., Novikov O,  Alamoud K, Koutrakis P, Mizgerd JP, Genco CA, O, Kukuruzinska MA, Monti S, Bais MV, and Sherr DH. 2016. The role of the aryl hydrocarbon receptor and its diverse ligands in oral cancer cell migration and tumorigenesis. Molecular Cancer Research, http://mcr.aacrjournals.org/content/14/8/696

Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Gusenleitner D, Li A, Monti S, Manteiga S, Lee K, and Sherr DH. 2016. An aryl hydrocarbon receptor-mediated positive feedback loop that enforces cell migration in ER/PR/Her2 human breast cancer cells. Molecular Pharmacology, https://www.ncbi.nlm.nih.gov/pubmed/27573671

Mulas F, Li A, Sherr DH, Monti S. 2016. Network-based analysis of transcriptional profiles from chemical perturbation experiments. BMC Bioinformatics. https://link.springer.com/article/10.1186/s12859-017-1536-9

Previously Reported Full Length, Peer Reviewed Journal Articles in Which Support from Find the Cause Was Acknowledged:

Smith, BW, Rozelle, SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Shui DHK, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton, DN, Mostoslavsky G, Sherr DH, and Murphy GJ. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. 2013. Blood: 122:376-385 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083512/

Quintana, F and Sherr, DH. 2013. Aryl Hydrocarbon Receptor Control of Adaptive Immunity. Pharmacological Reviews. 65:1148-1161 http://pharmrev.aspetjournals.org/content/65/4/1148

Monti, S and Sherr DH. 2013. The role of the aryl hydrocarbon receptor in normal and malignant B cell development. Seminars in Immunopathology 35:705-716. https://link.springer.com/article/10.1007/s00281-013-0390-8

Parks, A.,  Pollastri M, Frangs D,  Haigh-Molina S, Ashton T,  Ubellacker J, Stanford E
Schlezinger JJ, and Sherr DH. 2013. In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo. Mole. Pharmacol. 86:593-608 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201140/

Gusenleitner, D.,  Auerbach S, Tice R, Sherr DH, and Monti S. 2014. Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity. PLOS One. 9:e102579. https://www.niehs.nih.gov/news/newsletter/2014/9/science-newapproach/index.htm

Shivanna, S., Kolandaivelu K, Moshe S, Novikov O, Balcells M, Zheng A, Weinberg J, Francis J, Edelman ER, Sherr DH, and VC. Chitalia. 2016. The aryl hydrocarbon receptor is a critical regulator of tissue factor stability and is a novel anti-thrombotic target in uremia. J.Am.Soc. Neph. 27:189-201. PMC4696580 https://www.researchgate.net/publication/277409811_The_Aryl_Hydrocarbon_Receptor_is_a_Critical_Regulator_of_Tissue_Factor_Stability_and_an_Antithrombotic_Target_in_Uremia

Gross K, Wronski A, Skibinski A, Phillips S, Kuperwasser C: Cell fate decisions during breast cancer development. Developmental Biology 2015, 4:4. http://www.mdpi.com/2221-3759/4/1/4

Stanford E., Wang Z,  Novikov O, Mulas F, Landesman-Bolag E., Monti S, Smith B, Muprhy GJ, and Sherr DH. 2016. The role of the aryl hydrocarbon receptor in the development of cells with molecular and functional characteristics of breast cancer stem cells. BMC Biology. 16;14:20. doi: 10.1186/s12915-016-0240-y. https://www.ncbi.nlm.nih.gov/pubmed/26984638 

Stanford, EA, Ramirez-Cardenas, A, Wang, Z., Novikov, Alamoud, K, Koutrakis, P, Mizgerd, JP, Genco, CA, O, Kukuruzinska, MA, Monti, S, Bais, MV, and Sherr, DH. 2016. The role of the aryl hydrocarbon receptor and its diverse ligands in oral cancer cell migration and tumorigenesis. Molecular Cancer Research, https://tools.niehs.nih.gov/srp/researchbriefs/view.cfm?Brief_ID=262

Novikov O, Wang Z, Stanford EA, Parks AJ, Ramirez-Cardenas A, Gusenleitner D, Li A, Monti S, Manteiga S, Lee K, and Sherr DH. 2016. An aryl hydrocarbon receptor-mediated positive feedback loop that enforces cell migration in ER/PR/Her2 human breast cancer cells. https://www.ncbi.nlm.nih.gov/pubmed/27573671

2014-2016 List of Invited Lectures, Seminars, and Presentations at National or International Conferences at Which Find the Cause was Acknowledged:

2016     Harvard School of Public Health: “The role of an environmental chemical receptor, the AHR, in cancer stem cell production and invasion”, Boston, MA (Sherr)

2016     Boston University Research on Tap: “The computational genomics models of environmental chemical carcinogenicity ARC”, Boston, MA. (Monti, Sherr)

2016     International AHR Conference 2016, “AHR Control of Oral Squamous Cell Carcinoma Migration and Tumorigenesis”. University of Rochester School of Medicine, Rochester, NY. (Sherr)

2016     NIH/Library of Integrated Network-based Cellular Signals (LINCS) Retreat & Outreach Meeting, “High-throughput transcriptomic models for the fast and accurate prediction of chemical carcinogenicity and toxicity” UC Irvine, CA (Monti)

2016     University of Pavia, “High-Throughput Transcriptional Models of Chemical Carcinogenicity and Toxicity”, Pavia, Italy (Monti)

2016     Humanitas University, “High-Throughput Transcriptional Models of Chemical Carcinogenicity and Toxicity”. Milan, Italy (Monti)

2016     International Congress of Toxicology: “Identification and use of therapeutic AHR modulators”, Merida, Mexico (Sherr)

2016     NIH/Library of Integrated Network-based Cellular Signals (LINCS) Face-to-Face meeting, NIH campus, Bethesday, MD. (Monti, Sherr

2015     Evans Foundation Symposium, “Computational then cancer biology”, Boston, MA (Monti, Sherr)

2015     Pennsylvania State University. “The role of the aryl hydrocarbon receptor in cancer, blood cell specification, and thrombosis”, University Park, Pennsylvania (Sherr)

2015     Boston University Cancer Seminar Series: The Aryl Hydrocarbon Receptor, an Environmental Chemical Sensor, and Cancer. All Cancers?  Boston, MA (Sherr)

2015     Sterling Drug Distinguished Lecturer, Boston University School of Medicine, Pharmacology Department: “Why evolution saved the AHR”, Boston, MA. (Sherr)

2015     Superfund Research Program Annual Meeting, “Developing a computational framework for identifying and classifying modes of actions of chemical carcinogenicity in liver using gene expression profiling” San Juan, Puerto Rico (Li, Monti)

2014     National Society of Toxicology Symposium. Phoenix, Az. “The AhR controls breast cancer stem cell development and function” (Sherr)

2014     Society of Toxicology, Lone Star Regional Chapter, Austin, Tx. Keynote address: “The role of the AhR in environmental chemical receptor, in cancer stem cell biology”. (Sherr)

Scientist Published Papers